Basic Biology of Aging at the University of Washington

Genetic Approaches To Aging Training Grant

Supporting pre- and post-doctoral trainees through an NIA Training Grant.

Please see Pre-Doc Openingand Post-Doc Openings for info on upcoming open positions. For more application information and deadlines please see the application procedure.

Program Description

The goal of our program is to train new research scientists who will utilize contemporary genetic and molecular genetic techniques to investigate the underlying mechanisms of aging. The tools for the molecular genetic approach to the pathobiology of aging are becoming increasingly rich and diverse. We believe that this focus for gerontological research will be applied with increasing frequency and success, and that it is essential for our new investigators to be trained in their use.

Our faculty members are highly productive and interactive research investigators whose proficiencies encompassmost of the modern tools of molecular genetics. They are applying these approaches to analysis of fundamental cellular processes, such as DNA replication and repair, gene expression, protein homeostasis and stress response. In doing so, we will better understand the how these contribute to cellular and organismal aging. They work on a wide range of organisms amenable to genetic analysis, ranging from yeast, to C. elegans and Drosophila, to mouse and man.

We have in place a dynamic, comprehensive training program that brings together the disciplines of genetics, molecular biology and fundamental gerontological research. We have excellent investigators in these fields who collaborate extensively. Our faculty includes both senior members who have extensive experience in training predoctoral and postdoctoral students as well as newer members whom we believe are future leaders in aging research. The didactic component of this program is organized around a Basic Biology of Aging course, journal club and an annual seminar and proseminar series. Expertise in molecular genetics is taught predominantly by hands-on research in dynamic laboratories. All of our trainees carry out their research and didactic studies in an environment that regularly brings to their attention the exciting opportunities to apply genetic approaches to problems in gerontology.