Basic Biology of Aging at the University of Washington

Upcoming Speakers:

Symposium Registration Now Open: Healthy Aging in People & Their Pets
October 28-29, 2014 Hotel Deca, Seattle

For ​millions ​of ​people, ​pets ​are ​considered ​part ​of ​the ​family. ​ ​Unfortunately, ​companion ​animals ​such ​as ​dogs ​and ​cats ​age ​rapidly ​and ​have ​relatively ​short ​life ​expectancies. ​ ​ ​Research ​in ​the ​biology ​of ​aging ​has ​made ​tremendous ​strides ​over ​the ​past ​several ​years, ​with ​a ​few ​interventions ​having ​been ​found ​capable ​of ​slowing ​aging ​and ​extending ​healthy ​lifespan ​by ​20-40% ​in ​small ​mammals ​such ​as ​mice ​and ​rats. ​ ​These ​same ​interventions ​may ​be ​able ​to ​provide ​dogs ​and ​cats ​with ​three ​to ​five ​or ​more ​years ​of ​additional ​healthy, ​youthful ​life. ​ ​

This ​symposium ​will ​bring ​together ​experts ​in ​canine ​health ​with ​experts ​in ​the ​biology ​of ​aging ​to ​share ​their ​latest ​research ​discoveries ​and ​discuss ​how ​to ​best ​understand ​and ​tackle ​aging ​in ​companion ​animals. ​ ​Our ​primary ​goal ​is ​to ​accelerate ​translation ​of ​this ​science ​to ​promote ​healthy ​longevity ​not ​just ​in ​people, ​but ​also ​in ​our ​pets. ​

More Information and Registration

Genetic Approaches to Aging Trainee Research Presentations

Age is the single greatest risk factor for nearly every major cause of death and disability in developed nations, and promoting healthy aging is the most effective form of preventative medicine.  Yet, we typically don’t think about aging as a risk factor that can be modified. Research into the biology of aging is about to change that.

Trainees on the Genetic Approaches to Aging Training Grant utilize modern molecular and genetic approaches to investigate the underlying mechanisms of aging in order to help develop interventions that slow the aging process.  Come hear about the latest research in this fall’s Trainee Research Presentation Series:

All talks will be held in Foege N-130 (Bioengineering Conference Room)

Thurs. Oct. 23, 2:30-4:00pm

ALESSANDRO BITTO, PH.D.
Post-Doctoral Fellow, Kaeberlein Lab, Pathology
Effects of a high-dose rapamycin treatment on lifespan and healthspan in mouse
 JASON PITT, PH.D.
Post-Doctoral Fellow, Kaeberlein Lab, Pathology
Intermittent hypoxia therapy doubles lifespan in C. elegans

Thurs. Nov 20, 2:30-4:00pm

ADRIENNE WANG, PH.D
Post-Doctoral Fellow, Kaeberlein Lab, Pathology
Mitochondrial homeostasis in lifespan and disease
NATHAN BASISTY 
Pre-Doctoral Fellow, Rabinovitch Lab, Pathology
The changing landscape of poly-ubiquitin mediated homeostasis in aging, calorie restriction, and rapamycin treatment

Thurs. Dec 11, 2:30-4:00pm

KATE REID-BAYLISS 
Pre-Doctoral Fellow, Loeb Lab, Pathology
Measuring in vivo transcription fidelity
ANN CHIAO, PH.D. 
Post-Doctoral Fellow, Rabinovitch Lab, Pathology
Rejuvenating old hearts by interventions that enhance mitochondrial function

Past Speakers:

2014 Spring Quarter Speaker Series

The Nathan Shock Center of Excellence in the Basic Biology of Aging, the Genetic Approaches to Aging Training Grant, and the UW Healthy Aging and Longevity (HALo) Research Institute present:

All talks will be held in Room Foege N-130 from 2:30-3:30pm unless otherwise noted

Thursday, April 10
Selective autophagy: fighting aging one protein at a time
Ana Maria Cuervo,  M.D., Ph.D., Co-director of the Einstein Institute for Aging Research, Albert Einstein College of Medicine

Thursday, April 24
A metabolomic perspective on aging
Daniel Promislow, D.Phil., University of Washington, Director of the Canine Longevity Consortium

Thursday, May 8
Adaptive signaling responses to mitochondrial dysfunction: The mitochondrial UPR
Cole Haynes, Ph.D., 
Memorial Sloan Kettering Cancer Center

Thursday, May 22
Dynamic roles of mitochondria: from cancer to the aging immune system
Marcia Haigis, Ph.D., 
Harvard Medical School Department of Cell Biology

Thursday, June 5
Telomerase and germline immortality
Steven Artandi, Ph.D.,
Stanford School of Medicine

Wednesday, June 11, 3:30-4:30pm
Epigenetic changes leading to somatic retrotransposition in mammalian aging and a new genetic longevity model
John Sedivy, Ph.D.,
 Brown University