Basic Biology of Aging at the University of Washington

2012 Pilot Project Award and Application Process

Support for Studies In The Basic Biology of Aging (one year of support up to $35,000)

The University of Washington's Nathan Shock Center of Excellence in the Basic Biology of Aging will fund pilot research projects on basic research on the biology of aging. Applicants should be investigators at, or affiliated with, the University of Washington or the Fred Hutchinson Cancer Research Center. The application may either be designed to rapidly pursue a new finding or research opportunity, or to obtain preliminary data that will serve as a basis for a major research grant application. Junior faculty members are particularly encouraged to apply. While postdoctoral fellows cannot serve as Principal Investigators, they may receive support via faculty sponsors.

2011-2012 Awardees:

Leo Pallanck

Do PINK 1 and parkin influence the frequency of somatic mitochondrial DNA mutations?

Junior Faculty Award:

David Marcinek

Oxidative stress induces mitochondrial uncoupling and energy sensitive signaling in vivo in aged skeletal muscle

Dana Miller

 Mechanisms of environmental influence on protein homeostasis

Application Instructions

An abbreviated NIH-style application (face page/abstract/biosketch/other support and a six page maximum of narrative) is used. A cover letter should address the following questions:

  • How does this research specifically relate to the biology of aging?
  • Why do existing resources not permit the work to be done?
  • How will the pilot project facilitate future independent funding?
  • Suggestions of potential outside (non-UW) reviewers (up to 5). Please include the affiliation and contact information (phone, fax, email) and a list of any individuals to be excluded as potential reviewers.

For the research proposal, applicants should utilize the NIH Grant Form (PHS 398--RO1, in 12 point font or larger) of the National Institutes of Health, with the page restrictions described below. An EGC-1 form is not required. University internal applications for human subjects, recombinant DNA, hazardous materials or animal approval, if applicable, should be completed and attached.

Selection of awards will be based upon scientific merit and program relevance.

For more information contact Kathy Fawthrop 206-616-4135.

  1. Face Page (NIH Form, Page AA)
  2. Abstract (limited to 250 words) (NIH Form, Page 2)
  3. Budget (Direct Costs Only) (NIH Form, Page 4)
  4. Budget Justifications (Per NIH Guidelines)
  5. Biographical Sketch (NIH Form, Page 6)
  6. Other Support (NIH Form, Page 7)
  7. Research Plan (6 page maximum for sections a-d):
    1. Specific Aims (usually less than or equal to 1 page)
    2. Background and Significance (usually less than or equal to 1 page)
    3. Preliminary Studies (usually less than or equal to 2 pages)
    4. Research Design & Methods (usually less than or equal to 4 pages)
    5. Human Subjects (if applicable)
    6. Vertebrate Animals (if applicable, provide copy)
    7. Literature Cited (use full titles and page numbers)
    8. Consortium/Contractual Arrangements
    9. Consultants

Application Submissions

All Applications Due: March 30, 2012, 5:00 PM
Anticipated Date of Awards: July 1, 2012

Submit the cover letter and application electronically in PDF or Word format to:
Kathy Fawthrop, kathyfaw@u.washington.edu

Submit the original application plus five copies to:

Peter S. Rabinovitch, M.D., Ph.D.
University of Washington
School of Medicine
Health Science Building, K-081
Pathology, Box 357705
1959 NE Pacific Street
Seattle, Washington 98195-7705

For more information, please contact Kathy Fawthrop at 206-616-4135.

If you would like to be considered for Junior Faculty Support please email Peter Rabinovitch at:  petersr@uw.edu