Basic Biology of Aging at the University of Washington

Pilot Study and Junior Faculty Support
in the Basic Biology of Aging

Each year the University of Washington's Nathan Shock Center of Excellence in the Basic Biology of Aging funds three pilot research projects and/or Junior Faculty projects in the basic the biology of aging.

2014-2015 Awardees

Pilot Project:
Christine Queitsch
Assistant Professor, Genome Sciences
Chaperone contributions to longevity and mutation penetrance

Junior Faculty Support:
Carissa Perez Olsen, Basic Sciences, Fred Hutchinson Cancer Research Center
Understanding the Role of Plasmalogens in Membrane and Organismal Aging

Judit Villen, Assistant Professor, Genome Sciences
The Effects of Inhibiting TOR Signaling Pathway in Protein Homeostasis and Aging


2015-2016 Biology of Aging Applications Due: September 11, 2015, by 5:00 PM

Anticipated Date of Award: October 1, 2015


Special Funding Opportunity 2015-2016:

Pilot Study in the Biology of Aging in Alzheimer's Disease

The University of Washington’s Nathan Shock Center of Excellence in the Basic Biology of Aging supports research in the basic the biology of aging. This year we offer the special opportunity for funding of up to two $50,000 Pilot Project awards for basic research in the intersection of the biology of aging and Alzheimer’s disease. The Pilot Project application may be designed to rapidly pursue a new finding or research opportunity, or to obtain preliminary data that will serve as a basis for a major research grant application.

 Applicant Qualifications

  • Applicants should be investigators at, or affiliated with, the University of Washington.
  • Junior Faculty members are particularly encouraged to apply.
  • Postdoctoral fellows cannot serve as Principal Investigators for pilot projects. However, they may receive support via faculty sponsors.

Biology of Aging in Alzheimer's Applications Due: November 6, 2015, by 5:00 PM

Anticipated Date of Award: January 1, 2016. Funding period ends June 30, 2016.


Application Instructions

An abbreviated NIH-style application with cover letter is used.

Applications must include:

  • Cover letter which addresses the following questions:
    • Relation to the Biology of Aging: How does this research specifically relate to the biology of aging?
    • Need for Funding: Justify why this work cannot be completed with your existing resources.
    • Facilitation of Independent Funding: How will this support facilitate future independent funding?
    • Potential Reviewers: Suggestions of potential outside (non-UW) reviewers (up-to-5). Please include the affiliation and contact information (phone, fax, email) and a list of any individuals to be excluded as potential reviewers.
    • Junior Faculty members should specify if applying for either or both awards.
  • The National Institutes of Health Grant Form PHS 398-RO1 (in 12pt Times New Roman or 11pt Ariel or larger) with the page restrictions described below.
  • University internal applications for human subjects, recombinant DNA, hazardous materials or animal approval, if applicable, should be completed and attached.

Note: A University eGC-1 form is NOT required. 

NIH Form PHS 398-RO1 Page Restrictions

  1. Face Page (does NOT need to be signed by OSP) (NIH Form, Page AA)
  2. Abstract (limited to 250 words) (NIH Form, Page 2)
  3. Budget (Direct Costs Only) (NIH Form, Page 4)
  4. Budget Justifications (Per NIH Guidelines)
  5. Biographical Sketch (NIH Form, Page 6)
  6. Other Support (NIH Form, Page 7)
  7. Research Plan (6 page maximum for sections a-d):
    a. Specific Aims (usually less than or equal to 1 page)
    b. Background and Significance (usually less than or equal to 1 page)
    c. Preliminary Studies (usually less than or equal to 2 pages)
    d. Research Design & Methods (usually less than or equal to 4 pages)
    e. Human Subjects (if applicable)
    f. Vertebrate Animals (if applicable, provide copy)
    g. Literature Cited (use full titles and page numbers)
    h. Consortium/Contractual Arrangements
    i. Consultants

Selection of awards will be based upon scientific merit and program relevance.

Application Submissions

  1. Submit the cover letter and application electronically in PDF or Word format to:
    Ellen Cravens,
  2. Submit the original application plus five (5) copies to:
Peter S. Rabinovitch, M.D., Ph.D.
University of Washington
School of Medicine
Health Science Building, K-081
Pathology, Box 357705
1959 NE Pacific Street
Seattle, Washington 98195-7705

For more information, please contact Ellen Cravens 206-616-4135