Center Cores

Transgenic Animal Model Development Core A – Warren Ladiges

• Generation of conventional and allele replacement transgenic mouse models for studies of the biology of aging
• Assistance with study design and aging rodent colonies for studies of aging  

Functional Assessments Core B – Peter Rabinovitch     

• A comprehensive panel of physiologic and functional tests for the assessment of mouse "healthspan"
• An array of cellular assays for assessment of aging phenotypes, including flow cytometry and cell sorting, image cytometry and telomere analyses

Functional Genomics Core C – Michael MacCoss

• Proteomics, including measurements of proteome abundance and turnover Transcriptomics, including transcriptional arrays and Translational State Array Analysis (TSAA) Informatics
• Research Development 

Research Development Core D – Peter Rabinovitch and Matt Kaeberlein

• Support for pilot projects and junior faculty development in the biology of aging  

Program Enrichment Core E – Peter Rabinovitch and Matt Kaeberlein

• Support for seminars, courses, symposia and workshops
• Aging Genes/Interventions Database and Shared Resources Database
• Community outreach and collaboration with other Nathan Shock Centers   
• Administrative support