Namemec-1
OrganismCaenorhabditis elegans
Aging PhenotypeNo effect on life-span
Allele TypeRecessive
StrainBristol N2
DescriptionLoss of function mutations do not effect life span (Apfeld and Kenyon 1999).
Gene FunctionNot cloned.
Other PhenotypesMutants are touch insensitive, lethargic, and have displacement of some microtubule cells and amphidial neurons as well as defective fasciculation (Perkins et al., 1986).
HomologsN/A
Primary ReferenceApfeld, J., and Kenyon, C. (1999). Regulation of lifespan by sensory perception in Caenorhabditis elegans. Nature 402, 804-9. [Abstract]
Other ReferencesPerkins, L. A., Hedgecock, E. M., Thomson, J. N., and Culotti, J. G. (1986). Mutant sensory cilia in the nematode Caenorhabditis elegans. Developmental Biology 117, 456-487. [Abstract]
Relevant LinksWormBase: http://www.wormbase.org/db/gene/locus?name=mec-1;class=Locus
LocusLink: http://www.ncbi.nih.gov/LocusLink/LocRpt.cgi?l=188259
Keywordsneurons, Caenorhabditis, elegans, worm