NameBRE5
OrganismSaccharomyces cerevisiae (replicative)
Aging PhenotypeLife-span extension
Allele TypeDeletion
StrainBY4742
DescriptionDeletion of BRE5 increases yeast replicative life-span by approximately 30% (Kaeberlein et al., 2005).
Gene Function
Other Phenotypes
Homologs
Primary Reference
Other ReferencesKaeberlein, M., Powers, R. W., 3rd, Steffen, K. K., Westman, E. A., Hu, D., Dang, N., Kerr, E. O., Kirkland, K. T., Fields, S., and Kennedy, B. K. (2005). Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. Science 310, 119 [Abstract]
Relevant LinksUWAging: http://www.uwaging.org/ellison
SGD: http://db.yeastgenome.org/cgi-bin/locus.pl?locus=bre5
Keywordsnutrients, calorie restriction, caloric, yeast, genome-wide