Nameeat-7
OrganismCaenorhabditis elegans
Aging PhenotypeShortened life-span
Allele TypeRecessive
StrainBristol N2
DescriptionThe eat-7(ad450) allele decreases life span by 35% (Lakowski and Hekimi, 1998).
Gene FunctionNot cloned.
Other PhenotypesDefects in pharyngeal feeding behavior (Avery, 1993).
HomologsN/A
Primary ReferenceLakowski, B., and Hekimi, S. (1998). The genetics of caloric restriction in Caenorhabditis elegans. Proc Natl Acad Sci U S A 95, 13091-6. [Abstract]
Other ReferencesAvery, L. (1993). The genetics of feeding in Caenorhabditis elegans. Genetics 133, 897-917. [Abstract]
Relevant LinksWormBase: http://www.wormbase.org/perl/ace/elegans/gene/locus?name=eat-7
LocusLink: http://www.ncbi.nih.gov/LocusLink/LocRpt.cgi?l=267154
Keywordscaloric restriction, metabolism, Caenorhabditis, elegans, worm