NameCPR7
OrganismSaccharomyces cerevisiae (chronological)
Aging PhenotypeLife-span extension
Allele TypeDeletion
StrainW303
DescriptionDeletion of CPR7 increases chronological life-span (Harris et al., 2001).
Gene FunctionCyclophilin HSP90 co-chaperone.
Other PhenotypesDeletion of CPR7 has no effect on replicative life-span (Harris et al., 2001).
Homologs
Primary ReferenceHarris, N., MacLean, M., Hatzianthis, K., Panaretou, B., and Piper, P. W. (2001). Increasing Saccharomyces cerevisiae stress resistance, through the overactivation of the heat shock response resulting from defects in the Hsp90 chaperone, does not extend r [Abstract]
Other References
Relevant LinksSGD: http://db.yeastgenome.org/cgi-bin/SGD/locus.pl?locus=CPR7
Keywordsheat shock factor, HSF1, chaperone, stress resistance