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| | Name | ins-21 |
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| Organism | Caenorhabditis elegans |
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| Aging Phenotype | Life-span extension |
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| Allele Type | RNAi |
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| Strain | N2 rrf-3(pk 1426) |
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| Description | ins-21 was identified in a genomic screen for genes that are differentially transcribed in daf-16 and daf-2 RNAi animals (Murphy et al., 2003). RNAi of ins-21 increases life-span by 9%. |
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| Gene Function | Insulin/IGF-1-like peptide |
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| Other Phenotypes | |
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| Homologs | |
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| Primary Reference | Murphy, C. T., McCarroll, S. A., Bargmann, C. I., Fraser, A., Kamath, R. S., Ahringer, J., Li, H., and Kenyon, C. (2003). Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424, 277-83. [Abstract]
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| Other References | |
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| Relevant Links |
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WormBase: http://www.wormbase.org/db/gene/gene?name=ins-21
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LocusLink: http://www.ncbi.nih.gov/LocusLink/LocRpt.cgi?l=191689
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| Keywords | Caenorhabditis, elegans, worm, insulin, signaling, dauer, metabolism, daf-16, daf-2, microarray, transcription, genomics, gene expression, RNAi |
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