Namehsp68
OrganismDrosophila melanogaster
Aging PhenotypeLife-span extension
Allele TypeOverexpression
StrainarmGAL4
DescriptionOverexpression of hsp68 modestly (~15%) increases median and maximum life-span (Wang et al., 2003).
Gene FunctionChaperone.
Other PhenotypesHsp68 is activated by the JNK pathway.
Homologs
Primary ReferenceWang, M. C., D. Bohmann and H. Jasper, 2003 JNK Signaling Confers Tolerance to Oxidative Stress and Extends Lifespan in Drosophila. Dev Cell 5: 811-816. [Abstract]
Other References
Relevant LinksFlyBase: http://flybase.bio.indiana.edu/.bin/fbidq.html?FBgn0001230
LocusLink: http://www.ncbi.nih.gov/LocusLink/LocRpt.cgi?l=42852
Keywordsstress activated kinase, fly, heat shock