OrganismSaccharomyces cerevisiae (replicative)
Aging PhenotypeShortened life-span
Allele TypeDeletion
DescriptionDeletion of BUD1 shortens life-span (Jazwinski et al., 1998)
Gene FunctionGTPase involved in bud site selection.
Other PhenotypesBUD1 mutation result in a random budding pattern.
HomologsH.s. RAP1A, RAP1B, RAP2B ...
D.m. RAS3
S.c. RAS1, RAS2
Primary ReferenceJazwinski, S. M., Kim, S., Lai, C. Y., and Benguria, A. (1998). Epigenetic stratification: the role of individual change in the biological aging process. Exp Gerontol 33, 571-80. [Abstract]
Other References
Relevant LinksSGD:
Keywordsreplicative life-span, yeast, cell wall, morphology,