Intervention(R)-N-(2-heptyl)-N-methylpropargylamine
Alternate Name
OrganismDrosophila melanogaster
Aging PhenotypeNo effect on life-span
Allele TypeN/A
StrainOregon-R
DescriptionAdditon of 0.66 ng/fly/day (R)-N-(2-heptyl)-N-methylpropargylamine to a sucrose-based diet resulted in no significant effect on life-span (Jordens et al., 1999).
Gene FunctionMAO B (monoamine oxidase) inhibitor
Other PhenotypesLife-span reduction due to galactose feeding is partially suppressed by supplementation with (R)-deprenyl or (R)-N-(2-heptyl)-N-methylpropargylamine (Jordens et al., 1999).
Homologs
Primary ReferenceJordens, R. G., Berry, M. D., Gillott, C., and Boulton, A. A. (1999). Prolongation of life in an experimental model of aging in Drosophila melanogaster. Neurochem Res 24, 227-33. [Abstract]
Other References
Relevant Links
Keywordsselegiline, selegeline, SOD, superoxide dismutase, CAT, catalase, oxidative stress, oxidative damage, radicals, cancer, tumor, spleen, immune, humoral