InterventionGalactose feeding
Alternate Name
OrganismDrosophila melanogaster
Aging PhenotypeShortened life-span
Allele TypeN/A
StrainOregon-R
DescriptionReplacement of sucrose with galactose in the diet results in a significant shortening of mean and maximum life-span (Jordens et al., 1999)
Gene Function
Other PhenotypesLife-span reduction due to galactose feeding is partially suppressed by supplementation with (R)-deprenyl or (R)-N-(2-heptyl)-N-methylpropargylamine (Jordens et al., 1999).
Homologs
Primary ReferenceJordens, R. G., Berry, M. D., Gillott, C., and Boulton, A. A. (1999). Prolongation of life in an experimental model of aging in Drosophila melanogaster. Neurochem Res 24, 227-33. [Abstract]
Other References
Relevant Links
Keywordssugar, antioxidant, carbohydrate, diet, nutrition, fly