InterventionDNA and RNA Injection
Alternate Name
OrganismRattus norvegicus
Aging PhenotypeLife-span extension
Allele TypeN/A
DescriptionRats whose normal lifespan is 800-900 days were injected intraperitoneally with yeast DNA and RNA each week, starting at day 750 of their lives. This resulted in an approximately 100% extension in lifespan, to 1600-2200 days (0dens, 1973).
Gene FunctionN/A
Other PhenotypesCompared to saline-injected controls, treated rats ate more, gained body mass (controls lost weight), and appeared generally healthier and more active (Odens, 1973).
Primary ReferenceOdens, M. (1973). Prolongation of the life span in rats. J Am Geriatr Soc 21, 450-1. [Abstract]
Other ReferencesNone
Relevant LinksNone
KeywordsR. norvegicus, metabolism