InterventionDNA and RNA Injection
Alternate Name
OrganismRattus norvegicus
Aging PhenotypeLife-span extension
Allele TypeN/A
Strainunknown
DescriptionRats whose normal lifespan is 800-900 days were injected intraperitoneally with yeast DNA and RNA each week, starting at day 750 of their lives. This resulted in an approximately 100% extension in lifespan, to 1600-2200 days (0dens, 1973).
Gene FunctionN/A
Other PhenotypesCompared to saline-injected controls, treated rats ate more, gained body mass (controls lost weight), and appeared generally healthier and more active (Odens, 1973).
HomologsN/A
Primary ReferenceOdens, M. (1973). Prolongation of the life span in rats. J Am Geriatr Soc 21, 450-1. [Abstract]
Other ReferencesNone
Relevant LinksNone
KeywordsR. norvegicus, metabolism