InterventionMagnesium thiazolidine-4-carboxylic acid
Alternate Name
OrganismAedes aegypti
Aging PhenotypeLife-span extension
Allele TypeN/A
StrainUnknown
DescriptionDietary supplementation with magnesium thiazolidine-4-carboxylic acid results in a 30-40% increase in life-span (Richie et al., 1987).
Gene FunctionCysteine precursor.
Other PhenotypesTissue glutathione levels increased 50-100% upon supplementation with magnesium thiazolidine-4-carboxylic acid (Richie et al., 1987). Supplementation with magnesium chloride has no effect on life-span.
Homologs
Primary ReferenceRichie, J. P., Jr., Mills, B. J., and Lang, C. A. (1987). Correction of a glutathione deficiency in the aging mosquito increases its longevity. Proc Soc Exp Biol Med 184, 113-7. [Abstract]
Other References
Relevant Links
Keywordsantioxidant, SH, redox, reduction, oxidation