InterventionCDTA
Alternate Namecyclohexanediaminetetraacetatic acid
OrganismDrosophila melanogaster
Aging PhenotypeLife-span extension
Allele TypeN/A
StrainUnknown
DescriptionTreatment of files with CDTA inhibits the normal age-related cadmium accumulation and improves the median life-span by 20% (Massie et al., 1983).
Gene FunctionChelating agent.
Other PhenotypesDietary cadmium chloride at concentrations of 100 uM or greater shorten the life-span of Drosophila melanogaster by as much as 74% (Massie et al., 1983).
Homologs
Primary ReferenceMassie, H. R., Williams, T. R., and Aiello, V. R. (1983). Influence of dietary cadmium and chelators on the survival of Drosophila. Gerontology 29, 226-32. [Abstract]
Other References
Relevant Links
Keywordschelation, divalent ions, metals, Cd