InterventionTea extract
Alternate NameCamellia sinensis extract
OrganismDrosophila melanogaster
Aging PhenotypeLife-span extension
Allele TypeN/A
StrainOregon R
DescriptionDietary tea (Camellia sinensis) extracts were found to inhibit the ageing-related accumulation of iron and to prolong the life-span of Drosophila by as much as 21.4% (Massie et al., 1993).
Gene Function
Other PhenotypesThe life-span of Drosophila melanogaster (Oregon R) males was found to be proportional to the logarithm of the iron content of the diet. Life-span was also shown to be proportional to the rate of iron accumulation for Drosophila, mice and man (Massie et al., 1993).
Homologs
Primary ReferenceMassie, H. R., Aiello, V. R., and Williams, T. R. (1993). Inhibition of iron absorption prolongs the life span of Drosophila. Mech Ageing Dev 67, 227-37. [Abstract]
Other References
Relevant Links
KeywordsFe, calcium, Ca, ion