InterventionSodium citrate
Alternate Name
OrganismMytilina brevispina var redunca
Aging PhenotypeLife-span extension
Allele TypeN/A
StrainUnknown
DescriptionBrief immersion in a sodium citrate solution significantly extended life-span in the rotifer Mytilina brevispina var redunca (Sincock, 1975).
Gene FunctionChelating agent. Proposed to extend life-span by reduction of calcium accumulation (Sincock, 1975).
Other PhenotypesSimilar reductions in copper accumulation and life-span lengthening effects were observed after brief immersion in sodium tartrate, EDTA, or EGTA (Sincock, 1975).
Homologs
Primary ReferenceSincock, A. M. (1975). Life extension in the rotifer Mytilina brevispina var redunca by the application of chelating agents. J Gerontol 30, 289-93. [Abstract]
Other References
Relevant Links
Keywordsrotifer, chelation, divalent ions, metal, Cu