InterventionSodium cyanide
Alternate NameNaCN
OrganismSaccharomyces cerevisiae (chronological)
Aging PhenotypeLife-span extension
Allele TypeN/A
DescriptionIncubation in the presense of 250 uM NaCN increases stationary phase survival after 12 days (Fabrizio et al., 2003).
Gene FunctionNaCN is a respiratory inhibitor that reduces superoxide production.
Other Phenotypes
Primary ReferenceFabrizio, P., Liou, L. L., Moy, V. N., Diaspro, A., SelverstoneValentine, J., Gralla, E. B., and Longo, V. D. (2003). SOD2 Functions Downstream of Sch9 to Extend Longevity in Yeast. Genetics 163, 35-46 [Abstract]
Other References
Relevant Links
Keywordsrespiration, metabolism, Saccharomyces, cerevisiae, yeast, stationary phase, oxidative stress, mitochondria, uncouple