OrganismDrosophila melanogaster
Aging PhenotypeLife-span extension
Allele TypeOverexpression
StrainPdL x rtTA; Oregon-R x rtTA
DescriptionOverexpression of rdh from a doxycycline-inducible promoter results in a 6-17% increase in mean life-span (Landis et al., 2003).
Gene FunctionUknown.
Other PhenotypesRed herring is a previously unidentified open reading frame present in the first intron of the encore gene (Landis et al., 2003).
Primary ReferenceLandis, G. N., Bhole, D., and Tower, J. (2003). A search for doxycycline-dependent mutations that increase Drosophila melanogaster life span identifies the VhaSFD, Sugar baby, filamin, fwd, and CctI genes. Genome Biology 4, R8.
Other References
Relevant LinksLocusLink: