NameSug
OrganismDrosophila melanogaster
Aging PhenotypeLife-span extension
Allele TypeOverexpression
StrainPdL x rtTA; Oregon-R x rtTA
DescriptionOverexpression of sug from a doxycycline-inducible promoter results in a 5-9% increase in mean life-span (Landis et al., 2003).
Gene FunctionUnknown.
Other PhenotypesSugar baby is related to a maltose permease from Bacillus stearothermophilus.
Homologs
Primary ReferenceLandis, G. N., Bhole, D., and Tower, J. (2003). A search for doxycycline-dependent mutations that increase Drosophila melanogaster life span identifies the VhaSFD, Sugar baby, filamin, fwd, and CctI genes. Genome Biology 4, R8.
Other References
Relevant LinksLocusLink: http://www.ncbi.nih.gov/LocusLink/LocRpt.cgi?l=39314
FlyBasehttp://flybase.bio.indiana.edu/.bin/fbidq.html?FBgn0033782
Keywordsfly, sugar transport, carbohydrate transport