InterventionEGb 761
Alternate Name
OrganismCaenorhabditis elegans
Aging PhenotypeLife-span extension
Allele TypeN/A
StrainN2
DescriptionTreatment of worms with the Ginko Biloba extract EGb 761 increased median life-span by 8% (Wu et al., 2002). Treatment with the EGb 761 flavanoid component tamarixetin increased median life-span by 25%.
Gene FunctionEGb 761 is a standardized extract of Ginko Biloba leaves.
Other PhenotypesEGb 761 treatment increased resistance to acute oxidative and thermal stress by 33% and 25% (Wu et al., 2002).
Homologs
Primary ReferenceWu, Z., Smith, J. V., Paramasivam, V., Butko, P., Khan, I., Cypser, J. R., and Luo, Y. (2002). Ginkgo biloba extract EGb 761 increases stress resistance and extends life span of caenoraibditis elegans. Cell Mol Biol (Noisy-le-grand) 48, 725-31. [Abstract]
Other References
Relevant Links
Keywordsantioxidant, oxidative stress, reactive oxygen species