InterventionAntioxidant treatment
Alternate Name
OrganismRattus norvegicus
Aging PhenotypeNo effect on life-span
Allele TypeN/A
StrainLong Evans
DescriptionSupplementation of a standard diet with 2.5 g/kg coated ascorbic acid, 2 g/kg DL-alpha tocopherol (1100 U:g), 1 g/kg BHT, 0.1 g/kg beta carotene, and 0.02 g/kg menadione sodium bisulfite complex had no effect on life-span (Holloszy, 1998).
Gene FunctionAntioxidants and free-radical scavengers.
Other PhenotypesRats fed the antioxidant diet combined with voluntary wheel-running exercise lived longer than sedentary controls but failed to live longer than exercising rats fed a standard diet (Holloszy, 1998).
Primary ReferenceHolloszy, J. O. (1998). Longevity of exercising male rats: effect of an antioxidant supplemented diet. Mech Ageing Dev 100, 211-9. [Abstract]
Other References
Relevant Links
Keywordsantioxidants, exercise, free-radical, rats