InterventionD-glucosamine
Alternate Name
OrganismSaccharomyces cerevisiae (replicative)
Aging PhenotypeNo effect on life-span
Allele TypeDeletion
StrainW303R
DescriptionAddition of 0.5 mg/mL D-glucosamine to the growth media suppresses the short life-span of an mpt5 mutant, but fails to extend the life-span of wild type cells (Kaeberlein and Guarente, 2002).
Gene FunctionD-glucosamine is a precursor of chitin.
Other PhenotypesAddition of D-glucosamine to the growth media partially suppresses the temperature sensitive growth of an mpt5 mutant (Kaeberlein and Guarente, 2002).
Homologs
Primary ReferenceKaeberlein, M., and Guarente, L. (2002). Saccharomyces cerevisiae MPT5 and SSD1 Function in Parallel Pathways to Promote Cell Wall Integrity. Genetics 160, 83-95. [Abstract]
Other References
Relevant Links
KeywordsSaccharomyces cerevisiae, yeast, replicative, senescence, cell wall