Namefog-1
OrganismCaenorhabditis elegans
Aging PhenotypeNo effect on life-span
Allele TypeRecessive
StrainBristol N2
DescriptionThe fog-1(q180) allele has no effect on life-span (Arantes-Oliviera et al., 2002).
Gene FunctionRequired for the development of male germ cells.
Other Phenotypesfog-1 mutant animals are sterile and make oocytes but not sperm (Barton and Kimble, 1990).
HomologsS.c. HRP1, SGN1
S.p. Spbc660.15
C.e. CPB-1, CPB-2, CPB-3
R.n. HNRPAB
D.m. CG5735, ORB, CSTF-64
M.m. CPEB, HNRPAB, ELAVL1
H.s. HNRPAB
Primary ReferenceArantes-Oliviera, N., Apfeld, J., Dillin, A., and Kenyon, C. (2002). Regulation of life-span by germ line stem cells in Caenorhabditis elegans. Science 295. [Abstract]
Other ReferencesBarton, M. K., and Kimble, J. (1990). fog-1, a regulatory gene required for specification of spermatogenesis in the germ line of Caenorhabditis elegans. Genetics 125, 29-39. [Abstract]
Relevant LinksWormBase: http://www.wormbase.org/db/gene/locus?name=fog-1;class=Locus
LocusLink: http://www.ncbi.nih.gov/LocusLink/LocRpt.cgi?l=171895
KeywordsCaenorhabditis, elegans, worm, sterility