Namefer-15
OrganismCaenorhabditis elegans
Aging PhenotypeShortened life-span
Allele TypeRecessive
StrainBristol N2
DescriptionMutation of fer-15 results in a slight (~10%) reduction in mean life-span (Larsen and Clarke, 2002). Dietary restriction of coenzyme Q extends the life-span of fer-15 animals.
Gene FunctionInvolved in formation of spermatazoa
Other Phenotypesfer-15(b26ts) animals are temperature sensitive and sterile (Larsen and Clarke, 2002).
Homologs
Primary ReferenceLarsen, P. L., and Clarke, C. F. (2002). Extension of Life-Span in Caenorhabditis elegans by a Diet Lacking Coenzyme Q. Science 295, 120-3. [Abstract]
Other References
Relevant LinksWormBase: http://www.wormbase.org/db/gene/locus?name=fer-15;class=Locus
LocusLink: http://www.ncbi.nih.gov/LocusLink/LocRpt.cgi?l=267268
KeywordsCaenorhabditis, elegans, worm, sterility