Nameunc-7
OrganismCaenorhabditis elegans
Aging PhenotypeNo effect on life-span
Allele TypeRecessive
StrainBristol N2
DescriptionMutation has no effect on life span (Lakowski and Hekimi, 1998).
Gene FunctionOPUS/innexin family member. Required for coordinated locomotion.
Other PhenotypesMutants are uncoordinated (Brenner, 1974).
HomologsC.e. opu-1, unc-9, C18H7.2, F26D11.10, Y8G1A.2, T16H5 ...
D.m. inx2, inx7, CG1448, shakB, CG3039, 0gre ...
H.s. MRS1
Primary ReferenceLakowski, B., and Hekimi, S. (1998). The genetics of caloric restriction in Caenorhabditis elegans. Proc Natl Acad Sci U S A 95, 13091-6. [Abstract]
Other ReferencesBrenner, S. (1974). The genetics of Caenorhabditis elegans. Genetics 77, 71-94. [Abstract]
Relevant LinksWormBase: http://www.wormbase.org/db/gene/locus?name=unc-7;class=Locus
LocusLink: http://www.ncbi.nih.gov/LocusLink/LocRpt.cgi?l=181608
KeywordsCaenorhabditis, elegans, worm, caloric restriction, neurons