Nameunc-47
OrganismCaenorhabditis elegans
Aging PhenotypeNo effect on life-span
Allele TypeRecessive
StrainBristol N2
DescriptionThe unc-47(e367) allele has no signigicant effect on life span (Lakowski and Hekimi, 1998).
Gene FunctionVesicular GABA transporter.
Other PhenotypesMutants are uncoordinated (Brenner, 1974).
HomologsS.c. YJR100W, YNL101W, YKL146W, YEL064C, YER119C, YIL088C ...
S.p. Spbc1685.07c, CAA20055.1
C.e. T27A15, F59B2.2, Y4C6B.7, H32K16.1, F21D12.3, F15H10.4 ...
D.m. CG8394, CG6327, CG16700, CG7888, CG3424, CG12943 ...
R.n. Rn.10846
M.m. Viaat
H.s. FLJ10815, G17
Primary ReferenceLakowski, B., and Hekimi, S. (1998). The genetics of caloric restriction in Caenorhabditis elegans. Proc Natl Acad Sci U S A 95, 13091-6. [Abstract]
Other ReferencesBrenner, S. (1974). The genetics of Caenorhabditis elegans. Genetics 77, 71-94. [Abstract]
Relevant LinksWormBase: http://www.wormbase.org/perl/ace/elegans/gene/locus?name=unc-47
LocusLink: http://www.ncbi.nih.gov/LocusLink/LocRpt.cgi?l=176431
KeywordsCaenorhabditis, elegans, worm, caloric restriction, neurons