Nameunc-1
OrganismCaenorhabditis elegans
Aging PhenotypeNo effect on life-span
Allele TypeRecessive
StrainBristol N2
DescriptionMutation has no effect on life span. (Lakowski and Hekimi, 1998).
Gene FunctionUnknown.
Other PhenotypesMutants are uncoordinated (Brenner, 1974).
HomologsS.p. Spbc16G5.07c
C.e. Sto-4, Y71H9A, Mec-2, Sto-5, Sto-2, Sto-1, ...
D.m. CGt633, CG7635, CG17424, CG7468, CG14644, CG14736 ...
M.m. EPB7.2
H.s. EPB72, SRN1, SLP-1, SLP-2
Primary ReferenceLakowski, B., and Hekimi, S. (1998). The genetics of caloric restriction in Caenorhabditis elegans. Proc Natl Acad Sci U S A 95, 13091-6. [Abstract]
Other ReferencesBrenner, S. (1974). The genetics of Caenorhabditis elegans. Genetics 77, 71-94. [Abstract]
Relevant LinksWormBase: http://www.wormbase.org/db/gene/locus?name=unc-1;class=Locus
LocusLink: http://www.ncbi.nih.gov/LocusLink/LocRpt.cgi?l=180458
KeywordsCaenorhabditis, elegans, worm, caloric restriction, neurons