Namespe-10
OrganismCaenorhabditis elegans
Aging PhenotypeLife-span extension
Allele TypeRecessive
Strain
DescriptionMutation of spe-10 results in a 20% increase in mean life span on solid media (Cypser and Johnson, 1999).
Gene FunctionNot cloned.
Other PhenotypesMutants have a temperature sensitive defect in sperm development (Shakes and Ward, 1989). Life span correlates with thermotolerance and UV resistance (Cypser and Johnson, 1999).
HomologsN/A
Primary ReferenceCypser, J. R., and Johnson, T. E. (1999). The spe-10 mutant has longer life and increased stress resistance. Neurobiol Aging 20, 503-12. [Abstract]
Other ReferencesShakes, D. C., and Ward, S. (1989). Mutations that disrupt the morphogenesis and localization of a sperm- specific organelle in Caenorhabditis elegans. Dev Biol 134, 307-16. [Abstract]
Relevant LinksWormBase: http://www.wormbase.org/db/gene/locus?name=spe-10;class=Locus
LocusLink: http://www.ncbi.nih.gov/LocusLink/LocRpt.cgi?l=268146
KeywordsCaenorhabditis, elegans, worm, sterile