Namerad-8
OrganismCaenorhabditis elegans
Aging PhenotypeLife-span extension
Allele TypeRecessive
StrainBristol N2
DescriptionMutation of rad-8 increases life span by approximately 30% (Ishii et al., 1994)
Gene FunctionNot cloned.
Other Phenotypesrad-8 mutants are hypersensitive to UV radiation, but not X-rays or MMS (Hartman and Herman, 1982).
HomologsN/A
Primary ReferenceIshii, N., Suzuki, N., Hartman, P. S., and Suzuki, K. (1994). The effects of temperature on the longevity of a radiation-sensitive mutant rad-8 of the nematode Caenorhabditis elegans. J Gerontol 49, B117-20. [Abstract]
Other ReferencesHartman, P. S., and Herman, R. K. (1982). Radiation-sensitive mutants of Caenorhabditis elegans. Genetics 102, 159-78. [Abstract]
Relevant LinksWormBase: http://www.wormbase.org/db/gene/locus?name=rad-8
LocusLink: http://www.ncbi.nih.gov/LocusLink/LocRpt.cgi?l=268088
KeywordsCaenorhabditis, elegans, worm, DNA damage