InterventionPrevention of mating (by removal of females)
Alternate Name
OrganismDrosophila melanogaster
Aging PhenotypeLife-span extension
Allele TypeN/A
Strainunknown
DescriptionMortality of adult male flies increased strikingly in the presence of females (Finch, 1990; Partridge and Andrews, 1981). This increase was offset when female flies were separated from males at day 16 of the study (Finch, 1990; Partridge and Andrews, 1985).
Gene FunctionN/A
Other PhenotypesResearchers concluded that reproductive activity caused a major increase in mortality rate unrelated to senescence, although “no analysis was done to evaluate whether mortality rates were accelerated by mating (Finch, 1990).”
HomologsN/A
Primary ReferencePartridge, L., and Andrews, R. (1985). The effect of reproductive activity on the longevity of male Drosophila melanogaster is not caused by an acceleration of senescence. J. Insect Physio. 32, 925-929.
Partridge, L., and Andrews, R. (1981). Sexual activity reduces lifespan of male fruitflies. Nature 294, 580-582.
Other ReferencesFinch, C. (1990). Longevity, Senescence, and the Genome (Chicago: University of Chicago Press).
Relevant LinksN/A
KeywordsDrosophila, fly, D. melanogaster, fruitfly, reproduction, sterility