Namepetite
OrganismSaccharomyces cerevisiae (replicative)
Aging PhenotypeLife-span extension
Allele TypeRecessive
StrainYPK9, W303, SP1-1, A364A
DescriptionRespiratory deficient petite cells in strain YPK9 have a life span that is extended by ~35%. The relevance of this result is unclear, as the life span extension is strain specific. Petite cells in W303 have a life span identical to grande cells and petite cells in strains SP1-1 and A364A have a shorter life span than grande cells (Kirchman et al., 1999).
Gene FunctionN/A
Other PhenotypesRespiration defective petite cells have defective mitochondria and are unable to grow on glycerol.
HomologsN/A
Primary ReferenceKirchman, P. A., Kim, S., Lai, C. Y., and Jazwinski, S. M. (1999). Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae, Genetics 152, 179-90. [Abstract]
Other ReferencesNone.
Relevant LinksNone.
KeywordsMetabolism, Mitochondria, Oxidative stress, replicative senescence, Saccharomyces, cerevisiae, strain specific