Basic Biology of Aging at the University of Washington

Canine Longevity Consortium

Welcome to the home of the Canine Longevity Consortium (CLC). The consortium was created with the support of an R24 Network planning grant from the National Institute on Aging. The long-term goal of the CLC is to develop the domestic companion dog as a powerful model to better understand the biology of aging, the diagnostics of disease and the preservation of health.

Our mission is to design and implement a nationwide long-term longitudinal study of health and aging in companion dogs. We intend to follow 100,000 companion dogs over a 10-year period, with the goal of identifying the environmental and genetic determinants of healthy aging.

We are creating a collaborative, interdisciplinary network of researchers and clinicians throughout the country with the expertise needed to design and implement the first nationwide, Canine Longitudinal Aging Study (CLAS).

As part of our planning process, we are holding a series of meetings where we bring in experts from around the country. The specific goal of this meeting is to identify the challenges and opportunities that lie before us, as we apply existing technology, and develop novel IT solutions, to understand how and why dogs age. The meeting will include experts interested in applying IT solutions to collect and analyze electronic medical records, to carry out large-scale systems biology studies, to track environment, behavior, physiology, and health, and more. We are particularly interested in exploring the potential for mHealth solutions in companion dogs.

Why companion dogs? Our pet dogs live in the same environment as we do, they suffer from the same diseases, and the extent of the canine medical care system is second only to that for humans. Importantly, we can arrive at answers to our aging-related questions in dog models in just a few years, where it could take many decades in humans. Moreover, the IT solutions that we conceive of, develop and test in companion animals have a high probability of leading to solutions relevant to humans.

 

For more information, please contact the CLC Director, Dr. Daniel Promislow 

Our First Annual Meeting was held April 1-3, 2014 at the University of Washington, and included 37 scientists and veterinarians from throughout the United States. Our second meeting, held in Washington, D.C., in March of 2015, identified some key issues to address which spurred a technology-focused follow-up meeting in December 2015 in Seattle, Washington. Stay tuned for more information!

Director
Daniel Promislow, University of Washington 

Executive Committee

Steven Austad, University of Alabama

Nir Barzilai, AECOM, Yeshiva University

Adam Boyko, Cornell University

Kate Creevy, University of Georgia

Kimberly Greer, Prairie View A&M University

Dean Jones, Emory University

Matt Kaeberlein, University of Washington